Superliver (Liver Biopsy with Liver Staining Panel)
Test Code
CFBXLSP
Results:
3-5 business days.
Container
To prevent severe biopsy damage when temperatures are below freezing, we recommend adding 1:10 ratio of isopropyl alcohol (70% or greater) to 10% neutral buffered formalin.
Specimen
Submit liver tissue in 10% neutral buffered formalin, in a biopsy container available through ANTECH™ or other plastic, leak-proof, wide mouth 1 L or smaller container labelled with patients name, tissue source, and date.
Tissue specimens larger than 20 cm are most easily handled by sending them fresh: NO formalin, only enough saline to keep the sample moist, triple bagged to prevent leakage (leaks delay shipping), and refrigerated until pickup.
Test Description
Liver Biopsy with Liver Staining Panel.
A boarded pathologist with a special interest in canine and feline liver pathology will evaluate the tissue. Reports include: Source, microscopic description, microscopic findings and pathologist’s comments and direct contact information. In addition, where applicable reports include margin evaluation, tumor grading, and interpretation of special stains. Trichrome, rhodamine, and reticulum staining and interpretation are included. The report will include the staging of fibrosis, evaluation of the degree of parenchymal collapse, and a qualitative copper grade. Internal pathologist to pathologist opinions are sought when needed. There is an option for further discussion with an internal medicine consultant with a special interest in hepatic disease.
Note: Firmly and evenly tighten the lid of the formalin jar and check for any leaks prior to placing the sample in a Ziplock/sealable bag with the Test Requisition Form (TRF). A comprehensive history should be included with each biopsy submission, including the breed, age, and time when liver values were first noted to be elevated. Additional diagnostics performed as well as responses to any specific treatments should be included in the history.