Canine Cancer Diagnostics
CADET™ BRAF
Early and accurate detection of canine bladder and prostate cancer.

CADET™ BRAF
Accurate, affordable, and convenient
CADET™ BRAF evaluates canine urine samples for the presence of cells containing the b-raf mutation for the most common type of canine bladder/prostate cancer (transitionalcell carcinoma, also known as urothelial carcinoma TCC/UC). This cutting-edge technology is accurate, affordable, and convenient for both veterinarian and pet owner.
CADET BRAF can deted up to 85% of TCC/UC cases. For dogs without the b-raf mutation, Braf-Plus (a reflex test) can detect an even greater number of dogs with TCC/UC.
Reliable Accuracy
CADET BRAF detects up to 85% of TCC/UC cases in dogs.
For dogs without the b-raf mutation, Braf Plus (a reflex test) allows a greater number of TCC/UC patients be identified with just a urine sample.
Results are not impacted by the presences of red or white blood cells, protein, bacteria, or other potentially interfering substances which may impact urine testing.
How CADET BRAF is used in a clinical setting
Veterinarians can investigate for potential TCC/UC early in the course of the patient’s diagnostic workup. This is ideal for dogs presenting with abnormal urinary signs such as persistent hematuria, stranguria and recurrent or complicated urinary tract infections.
CADET BRAF can also be used as confirmation of TCC/UC diagnosis in cases for which cytologic findings are suspicious but not diagnostic for malignancy.
Webinar: Using Molecular Diagnostics to Detect Canine Bladder and Prostate Cancer
In this one-hour webinar with Dr. Sue Ettinger, DVM, DACVIM (Oncology), you will learn about detecting both prostate and bladder cancer in canines utilizing the CADET™ BRAF urine test. This test facilitates early diagnosis in clinical cases with recurrent, complicated, or antibiotic-resistant urinary tract infections presenting with hematuria without ultrasonographic evidence of a bladder mass. Dr. Sue Ettinger will share how this test simplifies diagnosing these rare cancers to achieve better health outcomes.
Clinical indications for usage of CADET BRAF
Clinical cases presenting with hematuria, stranguria, and/or urinary incontinence, with diagnostic imaging evidence of a mass in the bladder.
Confirmation of the TCC/UC diagnosis of a bladder mass from a stained cytology slide following ultrasonography and cytological examination of a fine-needle aspirate from tumor-bearing cells.
During chemotherapy, to monitor treatment success by decreased levels of BRAF mutation detection, or to monitor cancer relapse by recurrence of BRAF mutation tumor-bearing cells.
Early detection in high-risk dog breeds such as terriers, Shetland sheepdogs, Australian shepherds, cattle dogs, beagles, and border collies that are ≥6 years of age.
Early diagnosis in clinical cases with recurrent, complicated, or antibiotic-resistant urinary tract infections presenting with hematuria without ultrasonographic evidence of a bladder mass.

Antech™ Support
- Daily 6:00 a.m. to 5:00 p.m. MT
- Emergency support after hours