Please provide a copy of the original cytology report and
CSU submission form with your request.
1. Blood and bone marrow:
0.5 mL EDTA whole blood or bone marrow sample in lavender
top tube. 4-5 very cellular bone marrow slides can also be
submitted. Peripheral blood smears are not acceptable. If
available, please provide a complete blood count with
pathology review or cytology/histology report of the bone
marrow.
2. Lymph node and other organ aspirates:
Fluid in EDTA (lavender top tube) or 4-5 cellular slides
(smears or cytospins). No additional fluid (i.e.,
saline/serum) needs to be added to aspirated fluid. Stained
cytology slides are acceptable. Glued cover-slipped slides
cannot be used.
3. Body cavity fluid:
Fluid in EDTA (lavender top tube) or 4-5 cellular slides
(smears or cytospins).
Stained cytology slides are acceptable.
4. CSF:
Multiple cellular cytospin preparations are preferred
(stained or unstained) or fluid in EDTA (lavender top tube).
For the sample to be diagnostic, it is estimated that 50,000
lymphoid cells are needed. If the CSF has a lymphocyte count
of 100/uL, at least 0.5 mL of fluid is needed, or the cells
from 0.5 mL spun onto slides.
5. Formalin-Fixed Paraffin Embedded (FFPE) Tissue:
For this sample type, use code S86965 (Feline Intestinal
Lymphoma Panel performed at MSU) or S85562 (Lymphoma Panel
PARR, performed at MSU). If specifically requesting that
PARR testing be performed on FFPE tissue at CSU, please use
code S85503 and specify "FFPE tissue for CSU PARR"
Test Description
PARR (PCR for Antigen Receptor Rearrangement) is an assay that amplifies DNA. This test helps differentiate between monoclonal cells (most consistent with neoplasia) or polyclonal cells (most consistent with a reactive process).