Code
Test Description
* Indicates send out test
T550
Cryptococcus, Antigen
Specimen
1 ml serum or CSF
Method
ELISA
Schedule
12 working days
Indication
For the detection of Cryptococcal antigen.
Interpretive
Guidelines
This test is highly sensitive and specific for cryptococcosis.
Comments
A decline in titer of 24 fold per month indicates satisfactory response to treatment.
T790
Cryptosporidium & Giardia
Specimen
Feces
Method
FA
Schedule
2&150;3 working days
Indication
To rule out these parasites as a cause of chronic diarrhea.
T350
D-Dimer
Specimen
1 BT or 1 LT
Method
Latex agglutination
Schedule
Daily
Indication
Evaluation of bleeding disorders/investigation of DIC.
Interpretive
Guidelines
Increase supports a diagnosis of DIC.
Comments
Values of 250500 mg/dl may be seen in the post-surgical period.
T450
Dexamethasone Suppression Test (
Cortisol 3
)
Specimen
1 ml serum or heparinized plasma per tube, label tubes pre, 4 and 8 hour
Method
RIA
Schedule
Daily (
MSat
)
Indication
Low-dose Dexamethasone:
Test for hyperadrenocorticism (
Cushing's Syndrome
) in dogs, cats and horses.
High-dose Dexamethasone:
To differentiate pituitary dependent from adrenal tumor hyperadrenocorticism.
Interpretive
Guidelines
Low-dose Dex Suppression Test:
Normal:
Cortisol level less than 1.4 ug/dl 8 hrs post-dex.
Adrenal tumor (AT) or Pituitary Dependent (PDH):
Crotisol level greater than 1.4 ug/dl 8 hrs post-dex supports PDH.
PDH only:
Cortisol levels less than 1.0 ug/dl 26 hrs post-dex and greater than 1.4 ug/dl 8 hrs post-dex supports PDH.
NOTE
Approximately 5% of dogs with PDH have normal results. Alternatevly, false positive results may occur with stress or nonadrenal illness.
High-dose Dex Suppression Test:
Pituirary Dependent (PDH):
Cortisol level <1.4 ug/dl or <50% of baseline cortisol at 48 hrs.
Adrenal tumor (AT) or Pituitary Dependent (PDH):
Crotisol levels >1.4 ug/dl for the 8 ht testing period.
NOTE
A small percentage of PDH cases will not supress following a high dose of Dexamethasone.
Special Drawing Instructions:
Canine Low-dose
Dexamethasone
suppression
Test (LDDS):
Collect pre-sample; label tube "Pre-Dex".
Inject 0.01 mg/kg Dexamethasone IM or IV.
Collect 4 and 8 hr samples; label tubes accordingly.
Feline Low-dose
Dexamethasone Test:
Collect pre-sample; label tube "Pre-Dex".
Inject 0.01 mg/kg Dexamethasone IV.
Collect 4 and 8 hr samples; label tubes accordingly.
Canine High-dose
Dexamethasone Test:
Collect pre-sample; label tube "Pre-Dex".
Inject 0.01 or 1.0 mg/kg Dexamethasone IM or IV.
Collect 4 and 8 hr samples; label tubes accordingly.
Feline High-dose
Dexamethasone Test:
Collect pre-sample; label tube "Pre-Dex".
Inject 1.0 mg/kg Dexamethasone IV.
Collect 4 and 8 hr samples; label tubes accordingly.
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