Code Test Description * Indicates send out test   T010 Albumin   Specimen 1 ml serum, heparinized or EDTA plasma   Method Bromcresol Green dye   Schedule Daily   Indication To assess the quantity of this major protein which maintains colloid osmotic pressure and acts as a carrier protein for many other compounds.   Interpretive   Guidelines Decreased with renal or intestinal disease (increased loss), or hepatic disease (decreased production). Increase seen only with hemoconcentration due to dehydration.   Comments Hypoalbuminemia may result in edema/ascites. Hypoalbuminemia may result in a decrease of any compound carried by albumin (e.g. Calcium)   T215 ALK Phos Isoenzyme (Canine only)   Specimen 1 ml serum   Method Heat inactivation or Levamisole inhibition   Schedule 1–2 working days   Indication Measures corticosteriod induced fraction of alkaline phosphatase.   Interpretive   Guidelines Increased with corticosteroids, Cushing's or persistent stress.   T020 Alkaline Phosphatase   Specimen 1 ml serum or heparinized plasma   Method Kinetic/Bowers & McComb   Schedule Daily   Indication Evaluation of hepatic disease (esp. the biliary system), hyperadrenocorticism and, less commonly, bone disorders.   Interpretive   Guidelines Increased with cholestasis, any condition resulting in increased osteoblastic activity (e.g. fracture repair, bone neoplasms), phenobarbital or phenytoin medication, and corticosteroid excess.   Comments Young animals will often show an increase secondary to normal bone growth. In canines ONLY, there is a steroid-induced fraction (Cushing's, steroid therapy), which can be differentiated from the hepaticfraction by special testing (heat resistance test, levamisole inhibition test).   T030 ALT (SGPT)   Specimen 1 ml serum or heparinized plasma   Method Kinetic/Wroblewski & LaDue   Schedule Daily   Indication Evaluation of hepatic disease.   Interpretive   Guidelines Increase in this cytosolic enzyme indicates cell membrane damage and leakage, secondary hepatic infection, inflammation, trauma, neoplasia, anoxia/hypoxia and hepatoxic compounds (including a variety of drugs).   Comments Value does not necessarily correlate with the degree of hepatic insufficiency. A moderate increase may be induced by glucocorticoids or anti-convulsant madication. Severe muscle damage may cause ALT to increase. Please send comments to the webmaster. ©1997-2008 Antech Diagnostics, Inc. Site design and maintenance by amesDesign.