Antech Diagnostics Services Directory

Toxicology

Code

Test Description
* Indicates send out test

* S16055

Arsenic

Specimen

5 ml urine, 0.5 grams liver, stomach contents, hair, 0.5 grams kidney or 1 ml whole blood or serum

Method

AAS

Schedule

7–10 days

Indication

Suspicion of arsenic toxicity

Interpretive
Guidelines

Levels above baseline are consistent with arsenic toxicity.

T730

Bromide

Specimen

1 ml serum (Do Not Use SST)

Method

Gold trichloride

Schedule

1–3 days

Indication

To monitor anti-convulsant therapy

Interpretive
Guidelines

Low levels suggestive of inadequate anti-covulsant doses. High levels suggest toxicity.

T235

Cholinesterase

Specimen

1 ml serum or plasma

Schedule

3–7 days

Indication

Diagnosis of organophosphate toxicity

Interpretive
Guidelines

Cholinesterase is irreversibly inhibited by organophosphate-containing pesticides, but reversibly inhibited by carbamate insecticides. Low levels (< 25% of the normal range) support exposure.

* S16210

Copper

Specimen

1 ml serum or plasma

Method

Atomic absorption or ICP spectroscopy.

Schedule

5–10 days

Indication

To detect exposure to excessive copper levels or deficiencies.

Comments

Tissue levels are more useful for the diagnosis of storage disease. For dry weight copper levels request code S16215.

* S16215

Copper Storage Disease (Tissue Dry Weight)

Specimen

0.5 grams liver in fresh saline, fixed in 10% formalin or in paraffin block.

Method

Atomic absorption or ICP spectroscopy.

Schedule

7–10 days

Indication

To detect exposure to excessive copper levels or deficiencies.

S18702

Cyclosporine, baseline or post dose

Specimen

1 ml EDTA or heparinized whole blood. Draw post samples 6 hours following administration.

Schedule

7–10 days

T735

Digoxin, baseline or post dose

Specimen

1 ml serum (Do Not Use SST) Draw post samples 6 hours following administration

Method

RIA / TDX (fluorescent)

Schedule

1–2 days

Indication

To monitor digoxin therapy

Interpretive
Guidelines

Therapeutic serum digoxin concentrations should be monitored once a steady state is achieved (at least 6 days after commencing treatment). The optimal therapeutic range for Digoxin levels is 0.8 to 2.0 ng/ml at 6 to 8 hours post-administration. Digoxin levels > 2.5 ng/ml are commonly associated with toxic signs

Comments

1) The administration of diuretic or angiotensin converting enzyme (ACE) inhibitors, hypokalemia or azotemia will increase the frequency of digoxin toxicity; therefore, careful monitoring is necessary.
2) Minimal cross-reactivity for oleander toxicity.

T745

Lead, Blood

Specimen

1 LT or GRT

Method

Anodic stripping voltammetry (ASV)

Schedule

2–5 days

Indication

To detect exposure to lead.

Interpretive
Guidelines

Levels > 25 ug/dl indicate lead toxicity.