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Hematology
  Code Test Description
* Indicates send out test
  T340 Crossmatch (recipient/donor)
  Specimen 1 LT and 1 RT for recipient and 1 LT and 1 RT for donor
  Method RBC agglutination
  Schedule 1–3 days
  Interpretive
  Guidelines		 Agglutination or hemolysis indicates incompatibility with the donor.
  Indication Screen for host antibodies directed against antigens on the donor red cells.
  T345 Crossmatch (additional donor)
  Specimen 1 LT and 1 RT for recipient and 1 LT and 1 RT for donor
  Method RBC agglutination
  Schedule 1–3 days
  * S17501 Cytochemical Staining
  Specimen 2 LT and 3 to 4 fresh peripheral blood smears. Trasnport in slide holders.
  Method Chloracetate esterase, non-specific esterase, myeloperoxidase, Sudan, CD markers (CD3, CD 79a)
  Schedule 10–14 days
  Indication Acute leukemia cell type characterization.
  T350 D-Dimer
  Specimen 1 BT or LT
Allow vacuum of citrate tubes to deliver correct amount of whole blood, centrifuge, separate and place the citrated plasma in a tube with no anticoagulants or preservatives and cool. Please mark the tube as citrated plasma on the label.
  Method Latex agglutination
  Schedule Daily
  Indication Evaluation of coagulation disorders and investigation of possible DIC
  Interpretive
  Guidelines		 Increase values supports a diagnosis of DIC.
  Reference
  Ranges
Normal < 250 mg/dl
Mild elevation 250–500 mg/dl
Moderate elevation 500–1000 mg/dl
Marked elevation 1000–2000 mg/dl
Severe elevation > 2000 mg/dl
  Comments Values of 250–500 mg/dl may be seen in the post-surgical period.
  T540 Direct Coombs'
  Specimen 1 LT
  Method Agglutination
  Schedule 1–2 days
  Indication Investigation of autoimmune hemolytic anemia (AIHA)
  Interpretive
  Guidelines		 A positive test, in conjunction with appropriate clinical signs, is supportive of immune mediated hemolysis.
  Reference
  Ranges		 Negative
  * S16290 Erythropoietin
  Specimen 1 ml frozen serum or EDTA plasma.
Frozen: stable for 2 months at -20ºC
  Schedule 7–10 days
  Indication Evaluation of polycythemia
  Interpretive
  Guidelines		 Suppressed erythropoietin concentration in the presence of polycythemia supports a diagnosis of primary polycythemia (polycythemia vera). Normal or increased concentration indicates a secondary cause for polycythemia (hypoxia, renal cyst or tumor, hydronephrosis). This assay can also used in the evaluation of chronic renal disease, nonregenerative anemias and detect exogenous administration of EPOGEN.
  * S17509 Anti-Erythropoietin AB
  Specimen Serum
  Method ELISA
  Schedule 5–10 days
  Indication Detection of equine antibodies against human recombinant erythropoietin.
  Interpretive
  Guidelines		 A positive result implies previous exposure to hurEPO and exogenous erythropoietin administration.
  T365 Fibrinogen
  Specimen 1 BT (Preferred) or 1 LT within 24-hours of collection
  Method Automated
  Schedule Daily
  Indication Indirect indicator of inflammation.
  Interpretive
  Guidelines		 Fibrinogen levels increase in proportion to the severity and localized nature of the inflammatory process. Fibrinogen levels can decrease with DIC and hepatic failure.
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