Cats with suspected clinical toxoplasmosis should be administered supportive care as needed. Clindamycin hydrochloride administered at 12 mg/kg PO, q 12 hr for 4 weeks or trimethoprim-sulfonamide administered at 15 mg/kg, PO, q 12 hr for 4 weeks have been used most frequently. Axithromycin and doxycycline are potentially effective alternate treatments.